| Primary Identifier | MGI:4840370 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Igh-2-12Vh/Ighm)1Shc |
| Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene contains the unmutated, functionally rearranged immunoglobulin heavy-chain variable region segments, comprising V558(DSP2)J4, from the MRL/MP-Faslpr-derived hybridoma 2-12 joined to the mu constant region (Ighm) exons from BALB/c, which is of the Igha allotype. The encoded IGH chain, in combination with various immunoglobulin light chains, recognizes the nuclear antigen Sm and single stranded, but not double stranded, DNA. |
