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Allele : Trp53<tm1.1Xlu> transformation related protein 53; targeted mutation 1.1, Xin Lu

Primary Identifier  MGI:4840439 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 9 was replaced with one in which nucleotide substitutions (TCT-to-GCC) resulting in the amino acid substitution of serine with alanine at position 312 (p.S312A). A loxP site flanked neomycin resistance gene cassette inserted downstream of the modified exon 9 was removed by Cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Trp53<tm1.1Itl>,
  • p53<312A>,
  • S312A,
  • S312A,
  • p53<312A>,
  • Trp53<tm1.1Igl>,
  • Trp53<tm1.1Igl>,
  • Trp53<tm1.1Itl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele