Primary Identifier | MGI:4850024 | Allele Type | Targeted |
Gene | Hoxd13 | Transmission | Germline |
Strain of Origin | 129S2/SvPas | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The E. coli lacZ gene was inserted, with translational reading frames aligned, into the first exon of the mouse Hoxd11 gene in a construct containing the entire Hoxd11 transcription unit and its known cis-acting 5'and 3' regulatory sequences. This fusion gene, followed by a loxP-flanked PGK-neo selection cassette, was targeted to the intergenic region between the transcription initiation sites of Evx2 and Hoxd13, at the 5' extremity of the Hoxd complex. |