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Allele : Spdef<tm1Shiv> SAM pointed domain containing ets transcription factor; targeted mutation 1, Ramesh Shivdasani
Primary Identifier  MGI:4867866 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spdef
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2-5 were replaced with a PGK-neomycin resistance cassette. This removed the transactivation domain, the Pointed domain, and most of the Ets DNA binding domain. Absence of protein was confirmed by immunostaining.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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