Primary Identifier | MGI:4868388 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Flot1 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 3, and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Cre-mediated recombination removed exons 3 through 8 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. |