Primary Identifier | MGI:4868462 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(10Prmt2-Col6a1)1Yah |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | These mice were created using MICER targeting vectors. Prmt2 was targeted using a vector selected from the 3' HPRT library and the Col6a1 locus in cis was targeted using a vector selected from the 5' HPRT library. Mice carrying this construct were crossed with Tg(CMV-cre)1Ipc transgenic mice. Cre expression results in excision of a 0.5 MB segment of chromosome 10 containing 13 genes, 9 withknown functions. |