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Allele : App<tm1.1Ldad> amyloid beta precursor protein; targeted mutation 1.1, Luciano D'Adamio
Primary Identifier  MGI:4868766 Allele Type  Targeted
Gene  App Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 16 was replaced with a floxed neo cassette and a modified exon 16 in which a point mutation (ACC to GCC) results in the amino acid substitution of alanine for threonine at position 668 (T668A). Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • App<T668A>,
  • APP TA,
  • App<T668A>,
  • APP TA
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele




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