| Primary Identifier | MGI:4879001 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A construct containing a CAGGs promoter, a floxed neo stop cassette, an Fto cDNA, and an FRT flanked IRES-GFP cassette was inserted via homologous recombination. Cre mediated recombination removed the floxed neo-stop cassette. Heterozygous mice show about an 8 fold increase in protein expression in the pancreas. Homozygous mice show about an 11 fold increase in expression in skeletal muscle. |
