Primary Identifier | MGI:4880765 | Allele Type | Targeted |
Attribute String | Modified regulatory region, Null/knockout | Gene | Rr9 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = B6JN/1 mouse embryonic stem cells, derived from a (C57BL6/JJcl) x (C57BL6/NJcl) embryo |
molecularNote | The HS1, a conserved GATA3-response element upstream of the Il13 promoter that regulates expression of Il13 and Il4, was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. |