Primary Identifier | MGI:4888587 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Itgal |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector containing an I306A mutation in exon 9 and a self-excising loxP-flanked ACE (angiotensin-converting enzyme promoter)-cre-neomycin resistance cassette (also called ACN) in intron 9 was introduced to Bruce-4 C57BL/6-derived embryonic stem cells. Deletion of the floxed segment occurred during spermatogenesis, leaving a single loxP site. |