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Allele : Ank<tm1.1Ejr> progressive ankylosis; targeted mutation 1.1, Ernst J Reichenberger

Primary Identifier  MGI:4889192 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Ank
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A three base deletion of TTC at nucleotide positions 1130-1132 in exon 9 was created. This causes the deletion of phenylalanine at amino acid residue 377. At the same time, a floxed PGK neomycin selection cassette was inserted in intron 8 608 bp 5' of the TTC deletion. Founder mice were crossed to cre expressing mice in order to excise the selection cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ank<KI>,
  • Ank<KI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele