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Allele : Gpa33<tm1(GNAS)Wtsi> glycoprotein A33 transmembrane; targeted mutation 1, Wellcome Trust Sanger Institute

Primary Identifier  MGI:4889205 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence Gene  Gpa33
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing, a floxed IRES-neo/STOP cassette followed by an IRES and human GNAS with nucleotide substitutions that result in the amino acid subsitution of cysteine for arginine at position 201 (R201C), was inserted downstream of the coding sequence in exon 7. This mutation produces a constitutively active protein.
  • mutations:
  • Insertion
  • synonyms:
  • Gpa33<tm1(GnasR201C)Wtsi>,
  • Gpa33<tm1(GnasR201C)Wtsi>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele