Primary Identifier | MGI:4940364 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Zap70*M413A)2Weis |
Transmission | Germline | Strain of Origin | B6;129X1-Zap70<tm1Weis>/AnuApb |
Is Recombinase | false | Is Wild Type | false |
description | This BAC was microinjected into fertilized oocytes from B6.129-Zap70tm1Weis mice. |
molecularNote | Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-6m17) containing the entire mouse zeta-chain (TCR) associated protein kinase (Zap70) gene. A point mutation was introduced in exon 8, resulting in the substitution of a methionine for an alanine (M413A). |