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Allele : Tg(Upk3a-GFP/cre/ERT2)26Amc transgene insertion 26, Andrew P McMahon
Primary Identifier  MGI:4940379 Allele Type  Transgenic
Attribute String  Inducible, Recombinase, Reporter Gene  Tg(Upk3a-GFP/cre/ERT2)26Amc
Strain of Origin  (C57BL/6 x DBA)F1 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A targeting construct containing the eGF/cre/ERT2 (GCE) cassette and an FRT-flanked Kanamycin/neomycin selection cassette was inserted into the consensus start ATG codon of the Upk3a gene in a BAC (RP23-235E13). The PGK-Neo/Kan cassette was removed by transient Flpe-recombinase expression. The resulting BAC transgene was microinjected into (C57BL/6 x DBA) F1 donor eggs. Founder line 26 was subsequently established. Transgene expression is detected in the bladder urothelium and ureters of E15.5 embryos.
  • mutations:
  • Insertion
  • synonyms:
  • Upk3a-GCE,
  • Upk3a-GCE
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0 Mutation Involves

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