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Allele : Nlgn3<tm2Sud> neuroligin 3; targeted mutation 2, Thomas C Sudhof

Primary Identifier  MGI:4940397 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph, Reporter Gene  Nlgn3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The signal sequence coding region of exon 2 was replaced by preprotrypsin signal sequence followed by triplicated FLAG epitope coding sequence. Exons 2 and 3 were flanked by loxP sites and an FRT-flanked neomycin resistance cassette was placed in intron 2. Flp-mediated recombination removed the neo cassette. This allele is hypomorphic.
  • mutations:
  • Insertion
  • synonyms:
  • neuroligin-3 hypomorph,
  • neuroligin-3 hypomorph
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele