Primary Identifier | MGI:4941021 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Col2a1*R789C)#Waho |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | An Arg789Cys mutation (a C-to-T transition in exon 41) was engineered in the murine type II collagen (Col2a1). A second silent mutation was introduced to create a SmaI cleavage site in exon 41 used for monitoring the presence of the transgene. Five founders were created and progeny from two of these founders were analyzed. |