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Allele : Tg(Apoe-Pcsk9*H229A)#Prat transgene insertion, Annik Prat
Primary Identifier  MGI:4943505 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Apoe-Pcsk9*H229A)#Prat
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A Pcsk9 DNA construct with an H229A active site mutation was placed under the control of an Apoe promoter and a liver specific enhancer. mRNA expression was 40 fold higher than normal.
  • mutations:
  • Insertion
  • synonyms:
  • TgHA,
  • TgHA
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele




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