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Allele : Ttr<tm2.1(TTR)Kymm> transthyretin; targeted mutation 2.1, Ken-ichi Yamamura
Primary Identifier  MGI:4946280 Allele Type  Targeted
Attribute String  Inserted expressed sequence, RMCE-ready Gene  Ttr
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  ES cells containing the Ttrtm1Kymm null allele that serves as acceptor in recombination mediated cassette exchange were electroporated with a replacement vector and a cre recombinase expression vector. The replacement vector consisted of a wild-type human TTR cDNA and a FRT-flanked puromycin resistance gene flanked by a lox66 and a loxP site. Flp-mediated recombination removed the puro cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • I(-)P(-),
  • I(-)P(-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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