| Primary Identifier | MGI:4947240 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Jup |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 1, and a loxP site and an FRT-flanked neo cassette were introduced into intron 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. Cre mediated recombination removed exon 1. Western blot analysis of E12.5 homozygous embryos confirmed the absence of protein expression. |
