| Primary Identifier | MGI:4949110 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Grn |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites were inserted flanking exons 2 to 13 and a neo cassette was inserted downstream of the polyadenylation signal via homologous recombination. Cre mediated recombination removed exons 2 to 13. Western blot analysis confirmed the absence of protein expression in peritoneal macrophages from homozygous mice. |
