| Primary Identifier | MGI:4949709 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pikfyve |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cre-mediated recombination removed exon 6, which encodes the FYVE domain. This deletion is predicted to cause a frameshift and early stop codon. A 2-fold reduction in protein production was confirmed by western blot analysis of heterozygous mouse embryonic fibroblasts. |
