| Primary Identifier | MGI:4949646 | Allele Type | Targeted |
| Gene | Cacna1c | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This allele carries a premature stop codon, which results in the expression of C-terminally truncated protein (cutting 343 AAs; WT: 2139 AA, mutant: 1796 AA) at Gly-1796 with an extension of Leu-Ser-Lys-STOP, as well as an alternatively spliced, second variant ending at Gly-1796 with a LSATPERAREPR extension. The absence of the distal C-terminus peptide was confirmed by immunohistochemistry on heart sections. |
