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Allele : Gabra2<tm1.1Geh> gamma-aminobutyric acid type A receptor subunit alpha 2; targeted mutation 1.1, Gregg E Homanics

Primary Identifier  MGI:5000434 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gabra2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was designed (by site-directed mutagenesis) to substitute a serine to histidine at amino acid position 270 and leucine to alanine at amino acid position 277 of exon 9. An FRT-flanked PGKneo cassette was inserted downstream of exon 9. Flp-mediated recombination removed the neo cassette and left a single FRT site downstream of exon 9.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Gabra2<HA>,
  • Gabra2<HA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele