| Primary Identifier | MGI:5000435 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Gfap-gp120)#Lms |
| Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
| Is Wild Type | false |
| description | Phenotypic Similarity to Human Syndrome: Human Immunodeficiency Virus Infectious Disease J:170738, J:239462 (DOID:526). |
| molecularNote | The env gene from the LAV strtain of HIV-1 was truncated to encode gp120 amino acids 1-509 and inserted in exon 1 of a modified murine Gfap gene. Five lines (2, 3,10, 16, 37) were established which varied in level of expression. Level of expression did not correlate with transgene copy number. The pound symbol (#) is used when no line is specified and/or lines are pooled. |
