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Allele : Gja1<tm6.2(Gjb3)Kwi> gap junction protein, alpha 1; targeted mutation 6.2, Klaus Willecke

Primary Identifier  MGI:5004864 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gja1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites flank the coding region of Gja1. A single frt site remains immediately 3' of the polyadenylation signal as the result of FLP deletion of a frt-flanked neomycin resistance cassette from Gja1tm6(Gjb3)Kwi. The coding region and 88 bp of downstream sequence from Gja3 have been inserted between the Gja1 termination codon and its downstream DNA so that Cre recombinase mediated recombination will delete the Gja1 coding sequence and place that of Gja3 under control of the Gja1 regulatory sequences.
  • mutations:
  • Insertion
  • synonyms:
  • Cx43KICx43floxCx31,
  • Cx43KICx43floxCx31
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele