| Primary Identifier | MGI:5004867 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kpna6 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was replaced with a floxed neo cassette via homologous recombination. An alternatively spliced mRNA encoding for a protein lacking the importin beta-binding domain is produced. Only a truncated non-functional protein is found in homozygous mutant testes and mRNA levels are strongly decreased as transcription from testis-specific exon 1A does not occur. |
