Primary Identifier | MGI:5003453 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(PDGFB-APPSwDutLon)46Lpr |
Strain of Origin | CBA x C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human PDGF beta promoter drives expression of a human APP cDNA bearing 3 mutations Swedish (S: KM595/596NL), Dutch (D:E618Q), and London (L: V6421). This line has moderate overexpression of APP. |