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Allele : Pak2<tm1.1Rjak> p21 (RAC1) activated kinase 2; targeted mutation 1.1, Rolf Jakobi
Primary Identifier  MGI:5006978 Allele Type  Targeted
Attribute String  Not Specified Gene  Pak2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Nucleotide substitutions in exon 7 result in the amino acid substitution of asparagine for aspartic acid at position 212 (D212N). A floxed neo cassette was inserted downstream of the modified exon 7. Cre-mediated recombination removed the neo cassette and allowed for expression of the knock-in transcript. The knock-in product is caspase-cleavage deficient.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • PAK-2D212N-Neo-,
  • PAK-2D212N-Neo-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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