| Primary Identifier | MGI:5014071 | Allele Type | Transgenic |
| Attribute String | Transactivator | Gene | Tg(Fos-tTA)1Mmay |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Neuroscience Blueprint cre |
| molecularNote | The c-fos-tTA transgene was designed with the promoter region from the mouse FBJ osteosarcoma oncogene (Fos or c-fos; at least 611 bp of 5' untranscribed sequence that encompasses the known mouse c-fos regulatory elements) placed upstream of the tetracycline-regulated transactivator gene (tTA or "Tet-Off" ; flanked by an artificial intron and splice sites at the 5' end and by a polyadenylation signal from SV40 at the 3' end). Specifically, the tTA was inserted into the AccI site of the first exon of the mouse c-fos gene, |
