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Allele : Tg(CMV-CASP3)14Edge transgene insertion 14, Albert Edge

Primary Identifier  MGI:5014207 Allele Type  Transgenic
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter Gene  Tg(CMV-CASP3)14Edge
Strain of Origin  (C57BL/6 x C3H/HeN)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The Mos-iCsp3 transgene was designed with (from 5' to 3') a CMV promoter, a loxH site, a beta-galactosidase (lacZ) gene, a V5-tag (derived from the paramyxovirus of simian virus 5 (SV5)), a 6x-histidine-tag, a polyadenylation (polyA) signal, and a loxP. This floxed-lacZ-STOP cassette was followed by a myristoylation sequence, two tandem FK506-binding sites (Fvs), a human Caspase 3 (CASP3) gene, a haemagglutinin (HA) tag, and a second (polyA) signal. Lines 14 and 17 were generated.
  • mutations:
  • Insertion
  • synonyms:
  • Mos-iCsp3,
  • Mos-iCsp3
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele