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Allele : Slc4a7<Tg(Thy1-SNCA)12Mjff> solute carrier family 4, sodium bicarbonate cotransporter, member 7; transgene insertion 12, The Michael J Fox Foundation
Primary Identifier  MGI:5049859 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Slc4a7
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains the human alpha-synuclein (SNCA) gene driven by a mouse thymus cell antigen 1 (Thy-1) promoter. Line 12 inserted into the gene at 14719103-14719104 (Build GRCm38/mm10) resulting in a duplication. The duplication results in a functional knock-out of Slc4a7 in homozygous mice.
  • mutations:
  • Insertion,
  • Duplication
  • synonyms:
  • Tg(Thy1-SNCA)12Youy,
  • mThy1-hSNCA,
  • mThy1-hSNCA,
  • Tg(Thy1-SNCA)12Youy
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

3 Publication categories

Trail: Allele




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