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Allele : Aurkb<tm2.2Mama> aurora kinase B; targeted mutation 2.2, Marcos Malumbres

Primary Identifier  MGI:5056433 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Aurkb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 - 4 were flanked with wild-type and mutant loxP sites, an inverted IRES-lacZ cassette was inserted between exons 4 and 5 inside the loxP sites, and an FRT flanked neo cassette was inserted between exons 4 and 5 outside the loxP sites via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination inverted the IRES-lacZ cassette and removed exons 2 -4.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Aurkb(Z),
  • Aurkb(Z)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele