| Primary Identifier | MGI:5286114 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence, Reporter | Gene | Tg(Prnp-HTT*82Q,KRT14-EGFP)C63Dbo |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The mouse promoter drives brain-specific expression of the human cDNA encoding the first 586 N-terminal amino acids (N586) and an expansion of the glutamine tract to 82 (82Q). The transgene was co-integrated with a transgene in which the human promoter drives skin-specific expression fo EGFP. Lines C62 and C63 were generated with the later expressing at higher levels than the former. |
