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Allele : Gt(ROSA)26Sor<tm1.1(rtTA,EGFP)Nagy> gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Andras Nagy
Primary Identifier  MGI:5286599 Allele Type  Targeted
Attribute String  Reporter, Transactivator Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a floxed Pgk-neo-pA cassette and a rtTA-IRES-EGFP-pA cassette was inserted into intron 1 of the locus. Cre-mediated recombination removed the floxed neo cassette allowing the ROSA26 promoter to drive expression of rtTA and EGFP. Presence of doxycycline results in the formation of an active transcriptional activator and the activation of the responder transgene.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26rtTA,
  • ROSA26rtTA
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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