| Primary Identifier | MGI:5286986 | Allele Type | Transposon induced |
| Gene | Spink5 | Strain of Origin | FVB/N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A transposon transgene containing mouse Pgk2 driving expression of sleeping beauty 10 (SB10) and a mouse tyrosinase minigene driven by a Tyr enhancer flanked by Sleeping Beauty inverted repeats (termed pT-Tybs-3'E) were co-injected with a Pgk2 driven SB10. In line 1498, transposon and transposase co-integration results in a 66.8 kb deletion containing the coding exons of the targeted gene and none of the coding regions of the genes flanking the integration site. RT-PCR confirmed the absence of transcript expression at P0 skin cDNA. |
