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Allele : Lmx1a<tm1.1Tpe> LIM homeobox transcription factor 1 alpha; targeted mutation 1.1, Thomas Perlmann
Primary Identifier  MGI:5287979 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lmx1a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 1and a floxed neo cassette was inserted 288 bp downstream of exon 2 via homologous recombination. Cre mediated recombination deleted exons 1and 2, intron 1 and part of intron 2. Immunohistochemical analysis confirmed the absence of wild-type protein expression in the ventral midbrain of homozygous embryos at E11.5.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Lmx1a<->,
  • Lmx1a<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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