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Allele : Nr5a1<tm1.1Hain> nuclear receptor subfamily 5, group A, member 1; targeted mutation 1.1, Holly A Ingraham
Primary Identifier  MGI:5292676 Allele Type  Targeted
Gene  Nr5a1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The 2 SUMO consensus sites (K119 and K194) in exon 3 were mutated to arginine (R) residues and a floxed neo cassette was inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed the neo cassette. Tissues in homozygous mice showed a pronounced loss of sumoylated protein species.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Sf-1<2KR>,
  • Sf-1<2KR>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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