Primary Identifier | MGI:5293456 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CEPHY152F7)57Hgc |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene comprises a yeast artificial chromosome (YAC) from the CEPH Whole Genome MegaYAC Library carrying a 570-kb fragment of DNA from human Chromosome 21 that includes the potassium inwardly-rectifying channel, subfamily J, member 6 gene, KCNJ6 (also called GIRK2, KIR3.2 or HUM21ES123), which is expressed in the brain both in humans and in mice bearing the YAC as a transgene. Line 57 was shown by quantitative PCR analysis to carry two copies of the YAC. |