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Allele : Glra1<tm1.1Geh> glycine receptor, alpha 1 subunit; targeted mutation 1.1, Gregg E Homanics
Primary Identifier  MGI:5293666 Allele Type  Targeted
Attribute String  Not Specified Gene  Glra1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to insert a frt-flanked neomycin (neo) resistance cassette in opposite orientation to the gene, downstream of exon 7 of the glycine receptor, alpha 1 subunit (Glra1) gene. Nucleotide substitutions (CAG to ATC) introduced in exon 7 resulted in the amino acid mutation Q266I. Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • alpha1(Q266I),
  • alpha1(Q266I)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele




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