Primary Identifier | MGI:5295440 | Allele Type | Targeted |
Gene | Igh | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Site-directed mutagenesis introduced scrambled mutations of the 20 bp CTCF binding site 1 (CBE1) and 19 bp CBE2 sites within the intergenic control region 1 (IGCR1). Cre-mediated recombination removed the neo cassette inserted into the IGCR1. |