Primary Identifier | MGI:5296325 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Krt15-cre/ERT2)CNiem |
Strain of Origin | Not Specified | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A 5 kb Krt15 promoter fragment was inserted into a vector containing the cre/ERT2 (Cre/ER(G)T2) cassette. The construct was microinjected into oocytes and eight founder lines were obtained. 3 lines were found to exhibit specific cre nuclear staining patterns and recombined reporter patterns (in offspring of crosses) in hair follicles after tamoxifen administration. A high expressing line, line C, was established. |