|  Help  |  About  |  Contact Us

Allele : Ighm<tm1Bhe> immunoglobulin heavy constant mu; targeted mutation 1, Birgitta Heyman

Primary Identifier  MGI:5297544 Allele Type  Targeted
Attribute String  Not Specified Gene  Ighm
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A C to T point mutation was introduced into the gene coding for the third C domain of the mu-heavy chain causing the amino acid encoded by codon 436 to change from proline to serine. A floxed neomycin was inserted as well. This neo cassette was subsequently excised from correctly targeted mice.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Cmu13,
  • Cmu13
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele