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Allele : Gt(ROSA)26Sor<tm5(tetO-RNAi:T)Bgh> gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Bernhard G Herrmann
Primary Identifier  MGI:5297162 Allele Type  Targeted
Attribute String  Inducible, Knockdown, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Chimeric Strain of Origin  Not Specified
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  Both C57BL/6 and G4 Es cells were used for targeting.
molecularNote  Recombinase mediated cassette exchange was used to insert two short hairpin RNAi specific for the Brachyury (T) gene under the control of tetO followed by a PGK promoter into the Gt(ROSA)26Sortm2Bgh allele. Expression of the shRNAi requires treatment with doxycycline.
  • mutations:
  • Insertion
  • synonyms:
  • KD4-T,
  • KD4-T
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1 Feature

Trail: Allele

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1 Mutation Involves

Trail: Allele

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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