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Allele : Dock1<tm1.1Ysfk> dedicator of cytokinesis 1; targeted mutation 1.1, Yoshinori Fukui
Primary Identifier  MGI:5301316 Allele Type  Targeted
Gene  Dock1 Transmission  Germline
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  One loxP site was inserted upstream of exon 2 (containing the SH3 domain) and a floxed neomycin resistance cassette was inserted downstream. Mice were bred to Tg(EIIa-cre)C5379Lmgd expressing mice to excise exon 2 and the selection cassette. Normal transcription is observed on Northern blots but protein levels are less than 10% of levels in control mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Dock180<d>,
  • Dock180<d>
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Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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