| Primary Identifier | MGI:5301931 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Kcne1-cre/ERT2)1Imos |
| Strain of Origin | CD-1 | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The transgene construct was generated by BAC recombineering methods in bacteria. The Kcne1 (minK) coding sequence in BAC RP23276-120 was replaced with a cre/ERT2-bGH pA-Frt-Zeo-Frt cassette. The purified BAC was microinjected into fertilized CD-1 oocytes. Four founder lines that exhibited consisted inducible cre activity in the cardiac conduction were obtained. One line was analyzed in greater detail. Line numbers are not available. |
