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Allele : Tn(sb-SBlac)C.176599bFsp transposon insertion C.176599b, Francois Spitz
Primary Identifier  MGI:5305460 Allele Type  Transposon induced
Attribute String  Conditional ready, Reporter Gene  Tn(sb-SBlac)C.176599bFsp
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Mobilization of the transposon from TgTn(sb-SBlac)CFsp transgenic mice with Sleeping Beauty transposase from an unidentified line of TgTn(sb-SBlac)15Fsp transgenic mice results in the integration of the transposon at chr2:73958058-73958059 (GRCm39) in reverse (tel-cen) orientation. This location is in the gene desert between Atp5g3 and Lnp. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. LacZ expression is detected in the distal limbs and genital bud of E11.5 embryos.
  • mutations:
  • Transposon insertion
  • synonyms:
  • SB176599b,
  • HoxD<TpSB1>,
  • SB176599b,
  • HoxD<TpSB1>
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