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Allele : Del(2Evx2)51Ddu deletion, Chr 2, Denis Duboule 51
Primary Identifier  MGI:5305750 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(2Evx2)51Ddu
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A 550 kb deletion was induced by cre mediated recombination between Evx2/Hoxd13tm5.1(Hoxd11/lacZ)Ddu and Tn(sb-SBlac)C.176599bFsp . The deletion encompasses from just upstream of HoxD13 to the proximal half of the gene desert upstream of Lnp. At E12.5 mRNA expression of Hoxd13 is reduced to about one third wild-type level in the distal limbs. The deletion region includes the global control region (GCR), Prox regulatory element and regulatory islands III-V.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Del(Nsi-SB),
  • Del(Nsi-SB)
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1 Feature

Trail: Allele

Genome

0 Expresses

11 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele




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