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Allele : Del(2Atf2)52Ddu deletion, Chr 2, Denis Duboule 52
Primary Identifier  MGI:5305752 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(2Atf2)52Ddu
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A 590 kb deletion was induced by Cre-mediated recombination between Is(2)46Ddu and Atf2tm3Nicj. The deletion encompasses the entire gene desert upstream of Lnpk and part of Atf2. At E12.5 mRNA expression levels of Lnpk, Evx2, Hoxd13, Hoxd12, Hoxd11, and Hoxd10 are reduced to about 20% of wild-type levels in the developing digits.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Del(rel5-Atf2),
  • Del(rel5-Atf2)
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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