Primary Identifier | MGI:5305766 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(16Tiam1-Kcnj6)7Yey |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ES cells were targeted twice with MICER vectors inserting 403 kb upstream of the Tiam1 gene and 155 kb downstream of Kcnj6. Transient transfection using a cre-expression vector resulted in recombination between the two targeted sites creating a duplication/deficiency allele pair. |