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Allele : Tnfsf11<tles> tumor necrosis factor (ligand) superfamily, member 11; toothless

Primary Identifier  MGI:5307891 Allele Type  Chemically induced (ENU)
Attribute String  Dominant negative Gene  Tnfsf11
Strain of Origin  C57BL/6J x 129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  ENU-mutagenesis induced a point mutation (G to A) that results in the amino acid substitution of glycine with arginine at position 278 (p.G278R) in the encoded protein. The predicted protein is a dominant negative form.
  • mutations:
  • Single point mutation
  • synonyms:
  • RANKL<G278R>,
  • RANKL<G278R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele