Primary Identifier | MGI:5307891 | Allele Type | Chemically induced (ENU) |
Attribute String | Dominant negative | Gene | Tnfsf11 |
Strain of Origin | C57BL/6J x 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU-mutagenesis induced a point mutation (G to A) that results in the amino acid substitution of glycine with arginine at position 278 (p.G278R) in the encoded protein. The predicted protein is a dominant negative form. |